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Argireline Acetyl Hexapeptide-3 (aka Acetyl Hexapeptide-8) is most commonly known by the brand name Argireline (trade name of the Spanish cosmetics firm Lipotec) [3]

PD and FS wrote the manuscript with input from the other authors

doi: 10.2174/138920021705160324170558

In practice, simultaneous application is problematic: a 2022 Journal of Cosmetic Dermatology study found that applying both at the same time increased transepidermal water loss by 41% and produced 3.2 times more self-reported stinging compared to staggered application

Variable absorption based on product formulation

Supplementation supports immune health and lowers markers of oxidative stress