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This leads to the formation of secondary charged particles and free radicals within the cancer cell, subsequently interacting with DNA [89]

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In the 1990s and early 2000s, the exact binding site for IgG on FcRn and the 1:2 stoichiometry of the interaction were then revealed through the structural studies by Bjorkman and colleagues [24, 34,35,36, 97, 98]

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