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Most current therapeutic candidates for NDDs face challenges in crossing the bloodbrain barrier, substantially limiting their clinical efficacy (Ross and Poirier, 2004)

The cultures were subsequently incubated for 3 hours in a humidified CO 2 incubator (37C, 95% air and 5% CO 2 )

Graves disease The most common cause of hyperthyroidism is Graves disease

Peran L, Camuesco D, Comalada M, Nieto A, Concha A, Adrio JL, Olivares M, Xaus J, Zarzuelo A, Galvez J: Lactobacillus fermentum, a probiotic capable to release glutathione, prevents colonic inflammation in the TNBS model of rat colitis

doi: 10.1074/jbc.M103069200 134

Ferroptosis is an iron-dependent form of cell death, regulated through complex biochemical pathways and distinct from other cell death mechanisms like apoptosis and necrosis, both in its triggersiron accumulation and lipid peroxidationand outcomes [40, 41]