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A deeper mechanistic understanding of mitochondrial radioresistance will enable personalized radiotherapy regimens that exploit cancerspecific metabolic and apoptotic dependencies, ultimately improving outcomes for patients with treatmentresistant malignancies

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10.1038/ctg.2016.55 [DOI] [PMC free article] [PubMed] [Google Scholar] 36.To J, Issenman RM, Kamath MV

In this context "substantially free" of aggregates means that the amount of aggregates remains lower than 10%, 9%, 8%, 7%, 6%, 5%, 4%, 3%, 2% or 1 % (w/v), particularly also when being subjected to environmental stress, e.g

Vitamin in the crosshairs: targeting pantothenate and coenzyme a biosynthesis for new antituberculosis agents