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Therefore, the effect of l-Carnitine on autophagy induction in a given type of cell can differ depending on the circumstances, it can protect cells from damage either by increasing or suppressing autophagy induction in C2C12 cells

10.1248/bpb.b22-00174 47 Dubois-DeruyE.PeugnetV.TurkiehA.PinetF

It would be noteworthy for future studies to track carnitine levels of all patients who are taking valproic acid or carbamazepine over the course of the ketogenic diet and observe whether hypocarnitinemia is more prevalently developed in these subsets of patients over the course of the diet

Its role is to transport long-chain fatty acids into the mitochondria, where they can be used to produce energy

Puerarin inhibits FUNDC1-mediated mitochondrial autophagy and CSE-induced apoptosis of human bronchial epithelial cells by activating the PI3K/AKT/mTOR signaling pathway

Despite controlled inclusion criteria to minimize confounding factors, the limited sample size may have reduced the statistical power and robustness of the ROC results