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The broad knowledge accumulated regarding the pharmacokinetics of compounds and metabolites of Pycnogenol constitute a rational basis for effects characterized on a cellular level and observed in human clinical studies

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Chang et al., using proteomic techniques, compared the expression differences of TF and TfR1 in the brains and peripheral blood of normal mice and chronic social defeat stress (CSDS)-induced depression mouse models

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doi: 10.3389/fpsyt.2023.1195012 Received 27 March 2023 Accepted 09 May 2023 Published 02 June 2023 Volume 14 - 2023 Edited by Jeffrey A