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Availability: InStock
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To view a copy of this licence, visit About this article Cite this article Leung, J.M., Martinez, M.E

J., de Aguiar Vallim T

In experimental neuropathic pain models, repeated stimulation has been shown to downregulate pro-inflammatory cytokines (e.g., spinal IL-1, hippocampal TNF- ), upregulate IL-10, and suppress microglial and astrocytic activation, thereby fostering adaptive plasticity and reducing hypersensitivity (85, 86)