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An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: a report from a task force of the European Society for Clinical and Economic Aspects of osteoporosis and osteoarthritis (ESCEO)

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B1 Thiamine Energy metabolism and nerve function Thiamine is essential for converting carbohydrates into ATP the cellular fuel that powers every function in the body

It is likely that in individuals with glucose-6- dehydrogenase deficiency or NADPH-methaemoglobin-reductase deficiency the dyes would not be efficacious in reducing methaemoglobin (Brewer & Tarlov, 1961