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* Correspondence: Gbolahan O

Ethics declarations Conflict of interest Floriane Lignet, Manja Friese-Hamim, Frank Jaehrling, and Felix Rohdich are employees of the healthcare business of Merck KGaA, Darmstadt, Germany, and Samer El Bawab was an employee of the healthcare business of Merck KGaA, Darmstadt, Germany at the time of the study

14 Ferroptosis signaling pathways SLC7A11/GPX4 axis SLC7A11, also known as xCT, together with heavy chain subunit Solute Carrier Family 3 Member 2 (SLC3A2) form cystine-glutamate acid reverse transporter (System Xc - ), mediating the exchange of intracellular glutamate with extracellular cystine at 1:1

The GCH1/BH 4 /DHFR system suppresses ferroptosis The metabolic change that occurs in cancer cells often requires endogenous antioxidants to reduce toxic lipid oxidation

Journal of Sport and Health Science

Dietary antioxidants, circulating antioxidant concentrations, total antioxidant capacity, and risk of all-cause mortality: a systematic review and dose-response meta-analysis of prospective observational studies