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By 8 weeks, M B cells frequency dropped significantly, indicating that Gclc -deficient T1 B cells limit M B cells development and that Gclc is crucial for the transition from T1 to T2 B cells

Tan M, Yin Y, Ma X, Zhang J, Pan W, Tan M, et al

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[DOI] [PubMed] [Google Scholar] 120.Lushchak VI

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Under normal physiological conditions, about 3% of cytosolic glucose is processed via the polyol pathway, however, at higher concentrations of glucose, about 30% of the glucose enters the polyol pathway which makes it important in disposing of the glucose molecules and subsequent conversion to sorbitol [128]