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New insights in Type I and II CD20 antibody mechanisms-of-action with a panel of novel CD20 antibodies

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Taken together, this study provides immunogenicity assessment which is closely implicated with toxicokinetic study of GX-G3 in 4-week repeated administrated toxicological studies

Vinpocetine, a synthetic derivative of the vinca alkaloid vincamine, attenuated Mn-induced oxidative stress and apoptosis in rats ( Edaravone (Radicava), an FDA-approved drug for treating stroke and amyotrophic lateral sclerosis (ALS) ( In addition to its chelating properties on Mn, PAS exerted protective effects against Mn-induced neurodegeneration by enhancing antioxidant, anti-inflammatory, anti-excitotoxicity, and antiapoptotic effects in various in vitro and in vivo experimental models (Zheng et al., 2009