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The large localized production of superoxide will form a major sink to trap NO produced by any cell in the region and the peroxynitrite will react quickly in the immediate region because of the large local concentrations of carbon dioxide produced by activation of the hexose monophosphate shunt activated to supply NADPH needed for superoxide formation and NO synthesis

PLoS One 5 , e11552, (2010)

Vascular aging-driven erectile dysfunction: pathophysiological mechanisms and emerging therapies a narrative review

However, you cannot participate if you have been treated with certain medications for alcohol use disorder or carbonic anhydrase inhibitors within 30 days before starting the trial

Rev Soc Bras Med Trop (2020) 53:16

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