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Pathways affecting lipid metabolism and cell junctions, such as mitogen-activated protein kinase (MAPK) signaling, peroxisome proliferator-activated receptor (PPAR) signaling, tight junction, extracellular matrix (ECM)receptor interactions, focal adhesion, and regulation of the actin cytoskeleton, were suggested to potentially contribute to IMF deposition [29]

doi: 10.1016/j.yjmcc.2016.08.016 105 GuoB.ZhaiD

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Sethumadhavan S, Chinnakannu P: L-carnitine and alpha-lipoic acid improve age-associated decline in mitochondrial respiratory chain activity of rat heart muscle