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Integrative analysis of brain region-specific Shank3 interactomes for understanding the heterogeneity of neuronal pathophysiology related to SHANK3 mutations

Resveratrol (RSV), a natural plant antitoxin with probiotic activity, was found to attenuate TMAO-induced AS by lowering TMAO levels and increasing hepatic bile acid synthesis by remodeling the gut microbiota ( / mice fed a HFD, the abundances of Firmicutes and Verrucomicrobia were changed and the expression of hepatic FMO3 and serum TMAO levels were markedly reduced (Shi et al., 2018)