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In addition, it is more likely that single base mismatches can be determined with PNA/DNA hybridization because a single mismatch in a PNA/DNA 15-mer lowers the melting point (T.sub.m) by 8-20 C., vs

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10.1016/j.cell.2017.11.048 29 JiaM.QinD.ZhaoC.ChaiL.YuZ.WangW.et al (2020)

The peptide activates the VEGFR2-Akt-eNOS pathway and increases nitric oxide production, both of which stimulate blood vessel growth