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Directions for Use: Take one tablet daily with a glass of water, preferably with a meal

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However, in later stages of aggregation, TDP-43 affects LAMP2A peri-nuclear localization, leading to CMA-related lysosomal dysfunction (191)

We downloaded osteosarcoma cases from the TARGET database ( and the GEO database ( We excluded patients who lacked follow-up information or had unknown survival status, ultimately including a total of 139 cases in the survival analysis, consisting of 86 cases from the TARGET database and 53 cases from the GSE21257 dataset