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Tocochromanol uptake into enterocytes is facilitated by several transporters, including Niemann-Pick C1 like 1 (NPC1L1), scavenger receptor class B type I (SR BI), and cluster of differentiation 36 (CD36)

The microbiome-gut-brain axis: from bowel to behavior

Figure 9: Chronic liver disease (steatosis, steatohepatitis, and cirrhosis, respectively, based on severity of progression) is associated with decreased harvesting of energy and increased production of reactive oxygen species (ROS)

Gloss AD, Vasso DG, Hailey AL, Nelson Dittrich AC, Schramm K, Reichelt M

Supplementing with vitamin C, especially in individuals with suboptimal vitamin C levels or intake, increases glutathione levels

Specifically, sirtuin 1 (SIRT1) levels closely correlate with NSC activation, as SIRT1 levels are increased in activated NSCs