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Secondly, we aim to explore the roles of other hypoxia-related factors in the progression of AIDs, this includes a thorough analysis of the stability and activation mechanisms of HIF-2 under hypoxic conditions, and investigating the interactions and differences between HIF-2 and HIF-1 in the progression of AIDs, to optimize therapeutic outcomes and minimize side effects through the combined administration of HIF-1 and HIF-2 inhibitors (166)

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