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Insulin Sensitivity and Weight Management MOTS-C peptide improves glucose tolerance and limits weight gain in high-fat diet models

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By DNA fiber assay, we found that RNase H1 overexpression almost completely prevented replication fork slowing and sister fork asymmetry induced by HRASV12 or cyclin E1 overexpression in U2OS T-REx [RNH1-GFP] cells both 2 and 4 days after selection (Fig