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F., Laurent, D., Rothman, D

10.1016/j.cell.2012.03.042 Cell 34 DongX

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses

The other authors have no potential conflict of interest to declare

Discuss vial sizing with your prescriber and pharmacy

Silico docking (Schrodinger Inc., Small-Molecule Drug Discovery Suite, 2016-1) revealed that benserazide binds to the active site of CBS (PDB ID: 1JBQ) and reacts with the PLP cofactor to form a reversible but kinetically stable Schiff base, and its trihydroxybenzyl ring can form hydrogen bonds with polar residues located in the peripheral cavity (such as His203, Tyr223, and Tyr308), resulting in strong inhibition