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For example, serum ethylamine level was used as an indicator of L-theanine consumption, and the monitoring of 2,253 Japanese residents aged 4079 without diabetes found that a higher level of serum ethylamine was significantly correlated with a lower risk of type 2 diabetes, suggesting a negative association between L-theanine and diabetes (80)

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94 However, NAD increases also led to reduced activation of the WNT canonical pathway