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Unlike -KG, abnormal accumulation of succinate and fumarate in tumor tissues represses PHD, thus reducing HIF1 hydrolysis, suppressing demethylation of DNA and histones, and promoting the occurrence and development of tumors (Cavalli and Heard, 2009

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Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohns disease patients

J Nutr (2000) 130(4S Suppl):978S82S

These medications affect brain reward pathways that process food pleasure and cause delayed gastric emptying, which can create food aversions and alter taste perception