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Data availability Data that support the findings of this study are available upon reasonable request from the corresponding authors

Calcium, diacylglycerol, cAMP and various phosphate derivatives of myoinositol (phosphatidylinositol and others) are essential secondary messengers involved in the regulation of intracellular signaling cascades, in response to the activation of the TSHR, and are necessary for the production H 2 O 2 and TG synthesis (56)

JAMA Neurol 77(9):10891098 Schlmerich J, Fellermann K, Seibold FW, Rogler G, Langhorst J, Howaldt S, Novacek G, Petersen AM, Bachmann O, Matthes H, Hesselbarth N, Teich N, Wehkamp J, Klaus J, Ott C, Dilger K, Greinwald R, Mueller R, International TRUST-2 Study Group (2017) A randomised, double-blind, placebo-controlled trial of Trichuris suis ova in active Crohns disease

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