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These effects depend on integrin 1 and 1 pathway activation, creating functional outcomes of: Enhanced endothelial cell proliferation Increased cell migration to injury sites Improved tubule formation for angiogenesis No cytotoxic effects across wide concentration ranges Hair Follicle Stem Cells Hair follicle stem cells undergo amplification, demonstrated by follicle enlargement in mice

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Untreated HepG2 and HepG2 ATP7B-KO cells showed distinct expression profiles, with most genes upregulated in HepG2 and downregulated in HepG2 ATP7B-KO cells (Fig