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Souza MJD, Strock NCA, Ricker EA, Koltun KJ, Barrack M, Joy E, et al

Patients should discuss risks, contraindications, and alternatives with a licensed clinician

Long-term use: Clinical trials only ran 12 weeks, so long-term safety data (6+ months continuous use) comes from anecdotal reports

Concomitant medicines particularly insulin or sulfonylureas should be reviewed for interaction risk, and pregnancy or breastfeeding status should be assessed