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Stapled peptides for intracellular drug targets

Thus, ferroptosis can significantly alter the metastatic potential of cancer cells by affecting processes such as cytoskeletal remodeling and angiogenesis, offering new perspectives for cancer therapy

Das beeindruckendste Merkmal unserer Leber ist jedoch ihre Rolle als Entgiftungsorgan

KEAP1, which promotes the ubiquitination and subsequent degradation of NRF2, a key regulator of the antioxidant response, was upregulated in chemotherapy-sensitive tumors, suggesting that targeting the NRF2KEAP1 pathway could enhance the sensitivity of MIBC cells to cisplatin

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