interaction of chloroacetamide electrophiles with cellular glutathion Glutathione Dynamics in Subcellular Compartments and Implications for Drug Development Identification, optimization, and structural elucidation

Identification, optimization, and structural elucidation of chloroacetamide scaffold as covalent inhibitors for Ubiquitin C terminal Hydrolase L3 bioRxiv Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect Glutathione dynamics in subcellular compartments and implications for drug development ScienceDirect Characterization of glutathione proteome in CHO cells and its relationship with productivity and cholesterol synthesis Chevallier 2020 Biotechnology and Bioengineering Wiley Online Library New mechanistic insights into halogen dependent cytotoxic pattern of monohaloacetamide disinfection byproducts ScienceDirect Heat Shock Protein 90 Interactome Mediated Proteolysis Targeting Chimera (HIM PROTAC) Degrading Glutathione Peroxidase 4 to Trigger Ferroptosis Journal of Medicinal Chemistry

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