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[DOI] [PubMed] [Google Scholar] 69.Kujawska M., Bhardwaj S.K., Mishra Y.K., Kaushik A

These effects are mediated through inhibition of the NF-B/NLRP3/caspase-1 and Bax/Bcl-2/caspase-3 pathways, alongside activation of Nrf2/HO-1, p-AMPK, and -Klotho signaling (Khallaf et al

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Importantly, obesity can also worsen pre-existing T2 high asthma, highlighting that its impact is not limited to the obesity-driven asthma endotype but extends across asthma phenotypes [38]

Anticonvulsant activity and mechanism of actions of fractions of Ipomoea asarifolia (Desr)(Convolvulaceae) ethanol leaf extract

Firstly, beta cells rapidly release stored insulin from granules inside the cell Secondly, beta cells increase insulin synthesis for a smaller, second-phase release How Does Insulin Work