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They typically peak during dose escalation and ease as the body adapts to a stable dose

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This allows time for potential recurrence to manifest and be detected

Starting cagrilintide when already on retatrutide If you are already established on retatrutide at a stable dose (meaning you have been at your current retatrutide dose for at least four weeks without significant GI issues), you can introduce cagrilintide at its lowest starting dose of 0.25 mg weekly