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Mutations and overexpression of the -syn gene induce conformational changes, transforming soluble monomers into insoluble toxic aggregates

Role of TLR4 in the gutbrain axis in Parkinsons disease: a translational study from men to mice

Kendall, J.J

The elution gradient was a decreasing percentage of B from 80 to 4% during 17 min, holding at 5% of B for 3 min, and finally re-equilibrating the column at 80% of B for 4 min

Next, we performed competitive ABPP experiments by treating SK-MEL-103 cells first with either an SCLA compound or dimethylsulfoxide (DMSO), followed by treatment with a paired alkyne-modified clickable probe

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