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Turlin B, Mendler MH, Moirand R, Guyader D, Guillygomarch A, Deugnier Y (2001) Histologic features of the liver in insulin resistance-associated iron overload

This synthetic version of a naturally occurring peptide hormone in the body stimulates melanogenesis, or alpha-melanocyte stimulating hormone (MSH)

& Thorens, B

This leads to hypoxia, the release of various active substances, swelling of endothelial cells, increased nerve cell apoptosis, and even the formation of cerebral infarctions

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Consistent with glutamates key role in multiple aspects of brain physiology, metabolic studies have determined that virtually all of the glucose that enters the CNS is eventually converted to glutamate (Shen et al., 1999)