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This staggered treatment strategy may be clinically beneficial in maximizing efficacy while minimizing the potential increase in toxicity that might be anticipated from simultaneous co-treatment with two agents

Glioblastoma exhibits striking tumor heterogeneity leading to cellular hierarchies with self-renewing glioblastoma stem cells (GSCs), also known as brain tumor initiating cells (BTICs), at the apex

Due to its apparent superiority compared to conventional commercial encapsulation techniques, the potential benefits of SP@AMF in promoting a balanced gut microbiota and ensuring long-term safety make it a highly promising candidate for clinical implementation in the context of radiation therapy for abdominal/pelvic malignancies

The administration of the gamma subtype of peroxisome proliferator-activated receptors (PPAR) ligands has been demonstrated to reduce the production of inflammatory cytokines, such as IL-1 and TNF-, as well as inhibit the proliferation of inflammatory cells and the expression of specific adhesion molecules (305)

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Leifeld et al., 2022)