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apical to basolateral (A B) and basolateral to apical (B A) permeability compounds were added at 10 M concentration to the apical (A) side and basolateral (B) side, respectively, and the corresponding amount of permeation was determined by measuring compound concentration on the B or A side

in the absence of normal gut microbiota in the mouse dams, the expression of BEC claudin-5 and occludin is diminished and an increase in BBB permeability is observed in the offspring (Welcome, 2019)

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FIGURE 2 TIRAP (toll/interleukin-1 receptor domain-containing adapter protein) recruits MyD88 (myeloid differentiation factor 88) directly to the TLR4 cytoplasmic domain