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Additionally, exposure to AFB1 is associated with reduction in CNS phagocytic ability, increased levels nitrosative stress, increased expression of cytokines (TNF- and IL-1/6/8/10) (267), induced microglia cell apoptosis, dysregulation of p -NF-B signaling pathway (268), significant alteration in brain integrity, substantial DNA damage, S-phase cell cycle arrest (269), and other neuroimmunotoxic complications (245)

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via Antioxidative and Anti-Inflammatory Effects Reduces Stress-Induced Behavioral and Cellular Disorders in Mice

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The study also reported that rutin exhibits anti-inflammatory effects by inhibiting the production of inflammatory cytokines and enzymes

The polyphenols found in tea, especially green tea, can reduce digestion and absorption of carbohydrates, lipids and proteins and can affect gut microbiota and possibly the gutbrainliver axis (Reference Yang, Zhang and Zhang51)