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Biochim Biophys Acta 1760:7077

Diabetologia 60:15771585 Zhou G, Myers R, Li Y et al (2001) Role of AMP-activated protein kinase in mechanism of metformin action

This dual action strengthens the hair shaft, reduces breakage, and helps maintain hair density

ADP = adenosine diphosphate

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Interestingly, when measuring the levels of GSSG alone, no significant alterations were demonstrated in either HCT116 or SW837 cells following metformin treatment ( Figure 4B )