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Since egr-1 is critical in proliferation, differentiation, and inflammation during cholestatic liver injury, cytokine and growth factor generation and early extracellular matrix (collagen) formation (Kim et al., 2006

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Aivocode, the company developing CAQK, is currently seeking FDA authorization for Phase I clinical trials

GPX4 and GSH, as inhibitors of lipid peroxidation, are key regulators that control ferroptosis