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10.1172/jci.insight.151621 129 SilvaF

When activated by ROS or electrophilic substances, Nrf2 exits Keap1 and moves to the nucleus, functioning as a transcription factor to enhance the production of subsequent antioxidant and detoxi-fying enzymes like HO-1, NAD (P)H, NQO-1, SOD, and GSH-PX (112, 113)

The researchers envision that the ingestible capsule could be used at home by patients who need to take insulin or other injected drugs frequently

Molecular and Cellular Biochemistry, 195 (12), 219226

Other populations that may benefit from taking vitamin B12 include older adults, as this can counteract age-related absorption decline according to Agyeman