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Identifying the cause of vitamin B12 deficiency would enable tailoring the treatment with vitamin B12 (dose, frequency, route of administration, and duration)

Although dietary supplement use is discouraged by the NFLPA, supplements in some form are likely used by the majority of teams and players

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A 2022 CADTH review 1 performed at the request of GPAC found: No studies evaluating the clinical utility of B 12 testing in people with suspected B 12 deficiency