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The safety of Zepbound has been studied in clinical trials, and the results suggest that it can be an effective and relatively safe option for patients who meet specific criteria

Losses of B12 in adults approximate 13g/d (about 0.1% of body stores)

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It's usually treated with B12 injections or high-dose oral supplements, dietary advice, and, in some cases, proton pump inhibitors to reduce stomach acid levels