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GPx4 has been found to be elevated in hepatocellular carcinoma and colorectal carcinoma, whereas its expression is notably reduced in breast cancer and renal cell carcinoma compared with normal tissue (Sugezawa et al

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To investigate their biogenesis, we perform cryo-electron microscopy and liposome tubulation assays, showing that Arabidopsis SNX1 generates shorter membrane tubules than its mammalian counterpart, consistent with reduced membrane affinity linked to differences in the amphipathic helix

Vidmar Golja M, mid A, Karas Kueliki N, Trontelj J, Gerak K, Mlinari-Raan I

Thymoquinone inhibits matrix metalloproteinase expression in rabbit chondrocytes and cartilage in experimental osteoarthritis