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Description

Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degeneration

TB-500 protocols focus on frequency and cycle structure for sustained systemic signaling

DSIP is not approved for human use and is strictly intended for laboratory research only (RUO)

26042617, May 2015, doi: 10.1111/bph.13083

Their recently discovered enrichment in two additional layers within focal adhesions and their role in regulating myosin IB and IC affinity to actin suggest they modulate the precise dynamics of adhesion formation and turnover that is needed for persistent migration