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MDMA use also has a number of adverse health effects in the short term, including: Nausea Muscle cramping Blurred vision Chills or sweating Poor appetite Feelings of detachment Disorganized thoughts Increased heart rate Irritability Involuntary teeth clenching The effects of ecstasy usually begin after 20 minutes and last for about 3 to 6 hours

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*Correspondence: Yuying Fan [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers