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Aging Cell 21, e13725

10.1136/jitc-2023-007336 7 ChenG.XiongW.GuZ.GaoY.HouJ.LongL.et al (2022)

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Lets explore the temporal aspects of HCG dosing for TRT : Common Administration Schedules Twice Weekly Protocol Most widely adopted frequency Balances efficacy with convenience Typical doses: 250-500 IU per injection Thrice Weekly Protocol Used for more stable hormone levels May be beneficial for sensitive individuals Typical doses: 150-350 IU per injection Daily Micro-Dosing Less common but gaining traction Mimics natural hormonal patterns Typical doses: 50-100 IU daily Weekly Single Dose Least frequent administration May lead to more fluctuations Typical doses: 500-1000 IU once weekly The choice of frequency interplays with the HCG dose for TRT , creating a matrix of possibilities