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The reasons for these changes, apart from excess ROS leading to increased GSH depletion in cardiomyocytes, are disturbances in the anabolic process of GSH, causing a further decrease in intracellular GSH content

PMID: 29301816

doi: 10.1016/j.tibtech.2018.02.001 94 ZhangT.ZhuL.MadiganM

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doi: 10.3389/fendo.2022.1029210 Received 26 August 2022 Accepted 24 October 2022 Published 15 November 2022 Volume 13 - 2022 Edited by Ignacio Camacho-Arroyo, National Autonomous University of Mexico, Mexico Reviewed by Arturo Ortega, Centro de Investigacin y de Estudios Avanzados del Instituto Politcnico Nacional, Mexico