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People Taking Certain Medications Some commonly prescribed medications can deplete B12 over time

With any injections to the face, mild swelling and bruising are expected

The doctor must use a Medicare-approved laboratory service

Handling: Let cold or frozen vials warm to room temperature before opening so condensation wont form, and keep the solution clear of heat and direct light

Instead, hold the vial between your fingers and rotate it slowly in a circular motion, allowing the liquid to wash across the powder and dissolve it gradually

Reported side effects (rare): Mild fatigue Temporary nausea Injection site redness No known toxicity has been reported even at high doses in preclinical studies ( Toxicology Letters , 2022)