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Comparatively, aged macrophages are more sensitive to apoptotic signals as well [237]

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By: Matt Weik, BS, CSCS, CPT, CSN References Virmani, Mohamed Ashraf, and Maria Cirulli

Malonyl-CoA accumulates in the absence of fatty acids in these cells in an ACC-dependent manner (Supplemental Figure 4D), and labeling paralleled that of acetyl-CoA, suggesting that glucose-derived carbon may feed into an extramitochondrial acetyl-CoA pool in these cells (Figure 5C)

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Supports immune function and detoxification