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Wilson Theraputics developed this drug for the treatment of Wilsons disease

Despite decreased methylglyoxal detoxification capacity, cancers do not accumulate advanced glycation end-products

doi: 10.3389/fnins.2021.807988 75

[DOI] [PubMed] [Google Scholar] Koutsilieri, E

Intestinal oxidative stress associated with excessive ROS generation causes oxidative modifications to tight junction proteins leading to increased intestinal permeability, invasion of luminal bacteria, and gut dysbiosis