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Biochim Biophys Acta - Gen Subj 2009;1790:1486-1500

Science 369 , 10771084 (2020)

Serotonin decreases cytokines transcription, oxidative stress and APAP-adducts formation in the liver To assess whether cytokines concentrations induced by APAP in the serum are influenced by 5-HT levels, we measured TNF- and IL-6 concentrations in serum 24 hours following APAP administration

When starved of serine and glycine, all the cell lines showed a clear increase in de novo serine synthesis, as indicated by the accumulation of m + 3 labelled serine and m + 2 labelled glycine (Fig