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Vitamin D is the most studied approach

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[DOI] [Google Scholar] 65.Lopez A.B., Van Eck J., Conlin B.J., Paolillo D.J., ONeill J., Li L

80 Furthermore, EETs in renal tubules promote urinary Na excretion and attenuate sodium and water retention by inhibiting the activity of sodium channels

The compounds are then excreted via urine, serving to detoxify tissues, lower oxidative stress, and aid circulation, which could optimize heart and vascular health