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Vander Haar et al., 2007) and DEPTOR (DEP-domain-containing mTOR-interacting protein) (Peterson et al., 2009) interact with the complex via binding to RAPTOR and mTOR, respectively, and were shown to act as endogenous inhibitors of mTORC1 kinase activity

As OxS plays an important role in PSC activation and pancreatic fibrosis, we hypothesized that high glucose could stimulate pancreatic cells to produce excess ROS and activate PSCs, that induce pancreatic fibrosis and ultimately lead to -cell failure

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Mi XS, Zhong JX, Chang RC, So KF

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Dead space is the tiny volume of fluid left in the needle hub and the needle itself after the plunger is fully depressed